PRECLINICAL SCIENCE

In preclinical studies of mice, a gut bacterial strain releasing the two hormones induces a lowering of blood glucose, body weight and inflammation
but an increase of muscle- and bone mass

The recombinant bacterial peptide chosen for lead development
induces an increase of whole body insulin sensitivity and an increase in expression
of key genes involved in stimulation of thermogenesis, muscle cell differentiation
and bone formation but a suppression of hepatic glucose production

In preclinical studies of mice, a gut bacterial strain releasing the two hormones induces a lowering of blood glucose, body weight and inflammation but an increase of muscle- and bone mass

The recombinant bacterial peptide chosen for lead development induces an increase of whole body insulin sensitivity and an increase in expression of key genes involved in stimulation of thermogenesis, muscle cell differentiation and bone formation but a suppression of hepatic glucose production